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Cervical cancer, colposcopy, colposcopy-directed biopsy, and the unsatisfactory colposcopy.
Unsatisfactory colposcopy is a major problem in the diagnosis of cervical intraepithelial neoplasia (CIN). In previous studies of the unsatisfactory colposcopy, the frequency of unsatisfactory colposcopy varied from 4 to 34%, depending on the characteristics of the study population. The purpose of this study was to determine the frequency of unsatisfactory colposcopy in a consecutive series of 592 women and to identify significant risk factors for unsatisfactory colposcopy. The cervicovaginal smear, colposcopy, and colposcopy-directed biopsy were performed as a double-blinded diagnostic study. In total, 7.9% of the smears were unsatisfactory (squamous metaplasia or inflammatory process). The frequency of unsatisfactory colposcopy was 16.2% (n = 103), and the percentage of unsatisfactory colposcopy increased with the degree of squamous metaplasia, relative epithelial atypia, and col ac619d1d87
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